Mtor kinase inhibitors for oncology indications and diseases...

Details Mtor kinase inhibitors for oncology indications and diseases... Mtor kinase inhibitors for oncology indications and diseases...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2740975

Provided herein are Heteroaryl Compounds having the following structure: R2 N(I) or (II) wherein R1 -R4 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions, comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.

Cette invention concerne des composés hétéroaryle présentant la structure suivante : R2 N(I) ou B (II) où R1-R4 sont tels que définis dans le descriptif, des compositions comprenant une dose efficace dun composé hétéroaryle, et des méthodes de traitement ou de prévention du cancer, détats inflammatoires, de troubles immunologiques, de maladies dégénératives, du diabète, de lobésité, de troubles neurologiques, de maladies liées à lâge ou de pathologies cardiovasculaires, consistant à administrer une dose efficace dun composé hétéroaryle à un patient qui en a besoin.

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