A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/355 (2006.01) A61K 31/075 (2006.01) A61K 31/34 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/50 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2286341
A pharmaceutical combination formed of an MTP inhibitor and a fat soluble vitamin such as Vitamins E, A, K and/or D, and optionally another cholesterol lowering drug, is provided which is employed in a method for lowering serum lipids, cholesterol and/or triglycerides and thereby inhibiting or treating atherosclerosis, pancreatitis, hyperglycemia and/or obesity.
La présente invention concerne une combinaison pharmaceutique comprenant un inhibiteur de MTP (protéine de transfert de triglycéride microsomale) et une vitamine liposoluble telle que les vitamines E, A, K et/ou D, et, facultativement, un autre médicament permettant de réduire le cholestérol. Ladite combinaison pharmaceutique est utilisée dans un procédé destiné à réduire les taux sériques de lipides, de cholestérol et/ou de triglycérides et, ce faisant, à prévenir ou traiter l'athérosclérose, la pancréatite, l'hyperglycémie et/ou l'obésité.
Gregg Richard E.
Wetterau John R. II
Bristol-Myers Squibb Company
Cassan Maclean
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