C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 37/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2354644
The invention provides compounds and compositions of containing intracellular inhibitors of the mucin MUC-1. These intracellular MUC-1 inhibitors are exemplified by protein-based inhibitors that contain a targeting and/or an internalization domain, and by antisense nucleic acids. These inhibitors are useful in methods of treating autoimmune disorders.
L'invention porte sur des composés et compositions contenant des inhibiteurs intracellulaires de la mucine MUC-1. Lesdits inhibiteurs, par exemple des inhibiteurs à base de protéines contenant un domaine de ciblage et/ou d'internalisation ou des acides nucléiques antisens, peuvent s'utiliser dans des méthodes de traitement de troubles auto-immunitaires.
Agrawal Babita
Longenecker B. Michael
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biomira Inc.
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