A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/39 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C12N 15/62 (2006.01)
Patent
CA 2483473
The present invention provides compositions and methods for augmenting vaccine immunogenicity using mucin-immunoglobulin fusion proteins. The vaccine of the invention comprises: (a) an adjuvant polypeptide comprising a first polypeptide operably linked to a second polypeptide, wherein the first polypeptide is a mucin polypeptide and is glycosylated by a alpha 1,3 galactosyltransferase and the second polypeptide comprises at least a region of an immunoglobulin polypeptide and, (b) an antigen.
La présente invention concerne des compositions et des procédés destinés à augmenter l'immunogénicité de vaccins à l'aide de protéines hybrides mucine-immunoglobuline.
Recopharma Ab
Ridout & Maybee Llp
LandOfFree
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