C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/00 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) C07K 7/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) A61P 11/12 (2006.01) C12N 9/12 (2006.01)
Patent
CA 2595406
Peptides are provided that comprise less than 24 amino acids. The peptides have an amino acid sequence selected from the group consisting of: (a) an amino acid sequence having from 4 to 23 contiguous amino acids of a reference sequence PEPTIDE 1; (b) an amino acid sequence substantially identical to the sequence defined in (a); and (c) a variant of the amino acid sequence defined in (a). Also provided is a non-myristoylated MANS peptide. Various methods of using the peptides are also provided.
L'invention concerne des peptides qui comprennent moins de 24 acides aminés. Ces peptides présentent une séquence d'acides aminés choisie dans le groupe constitué par: (a) une séquence d'acide aminé comprenant de 4 à 23 acides aminés contigus de la séquence de référence PEPTIDE 1; (b) une séquence d'acides aminés sensiblement identique à la séquence définie dans (a); et (c) un variant de la séquence d'acides aminés définie dans (a). L'invention concerne également un peptide MANS non myristoylé. Diverses méthodes d'utilisation de ces peptides sont en outre décrites.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biomarck Pharmaceuticals Ltd.
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