C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/63 (2006.01) A61K 38/17 (2006.01) C07K 14/21 (2006.01) C07K 14/315 (2006.01) C12N 5/10 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2514986
The present invention discloses open reading frames (ORFs) in human genome encoding for novel mucin-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of disease.
La présente invention concerne des cadres ouverts de lecture (ORF) dans un génome humain codant de nouveaux polypeptides de type mucine, et des réactifs en relation avec lesdits cadres comprenant des variants, des mutants et des fragments desdits polypeptides, ainsi que des ligands et des antagonistes dirigés contre eux. L'invention concerne également des procédés d'identification et de fabrication de ces molécules, de préparation de compositions pharmaceutiques les contenant et de leur utilisation dans le diagnostic, la prévention et le traitement de maladies.
Bienkowska Jadwiga
Mcallister Gregg
Applied Research Systems Ars Holding N.v.
Kirby Eades Gale Baker
LandOfFree
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