A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 39/39 (2006.01) C07H 21/02 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01)
Patent
CA 2443045
An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and methods of use. The peptide or polypeptide may be conjugated to a carrier protein and administered as part of a vaccine or immunogenic composition for prevention or treatment of a disease or disorder.
L'invention concerne un peptide ou polypeptide isolé renfermant la séquence VSIGLSFPMLP (SEQ ID NO:1), trouvée dans la forme sécrétée de la MUC1 humaine, lequel peptide ou polypeptide qui facilite une réponse immunitaire lorsqu'il est administré à un animal. Cette invention concerne également des compositions contenant ce peptide, des cellules hôtes produisant ce peptide et des procédés d'utilisation. Ce peptide ou polypeptide peut être conjugué à un porteur et administré en tant que composante d'une composition vaccinale ou immunogénique pour la prévention ou le traitement d'une maladie ou d'un trouble.
Dorsey Mantley Jr.
Herbert Lynn
Hnatyszyn James H.
Kraus Gunter
Lopez Diana M.
Sim & Mcburney
The University Of Miami
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