Mucin synthesis inhibitors

Details Mucin synthesis inhibitors Mucin synthesis inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/02 (2006.01) A61K 31/192 (2006.01) A61K 31/365 (2006.01) A61K 31/41 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/443 (2006.01) A61K 31/444 (2006.01) A61K 31/675 (2006.01) A61K 31/724 (2006.01) A61K 45/06 (2006.01) C07C 229/52 (2006.01) C07D 213/643 (2006.01) C07D 213/74 (2006.01) C07D 307/88 (2006.01) C07D 401/02 (2006.01) C07D 405/06 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2505557

The claimed invention relates to methods of modulating mucin synthesis and the therapeutic application of compounds in controlling mucin over-production associated with diseases such as chronic obstructive pulmonary diseases (COPD) including asthma and chronic bronchitis, inflammatory lung diseases, cystic fibrosis and acute or chronic respiratory infectious diseases.

L'invention porte sur des procédés de modulation de synthèse de la mucine et sur les applications thérapeutiques des composés dans le contrôle de la surproduction de la mucine associée à des maladies telles que les broncho-pneumopathies chroniques obstructives (BPCO) dont l'asthme et les bronchites chroniques, les maladies pulmonaires inflammatoires, les fibroses cystiques et les maladies infectieuses respiratoires aiguës ou chroniques.

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