A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/02 (2006.01) A61K 9/00 (2006.01) A61K 47/32 (2006.01) A61K 9/70 (2006.01)
Patent
CA 2331350
This invention pertains to mucoadhesive compositions for the delivery of pharmacologically active agents, and to polymeric formulations that allow for a prolonged, sustained release of the active agents. More specially the invention pertains to compositions for the delivery of drugs to mucosal tissue, said composition comprising a drug or a plurality of drugs to be delivered and a thermoplastic graft copolymer, said graft copolymer being the reaction product of a polystyrene macromonomer having an ethylenically unsaturated functional group, and at least one acidic hydrophilic monomer having an ethylenically unsaturated functional group.
La présente invention concerne des compositions mucoadhésives, destinées à administrer des agents actifs sur le plan pharmaceutique, qui permettent une libération lente et prolongée des agents actifs. L'invention concerne plus spécifiquement des compositions destinées à administrer des médicaments aux muqueuses, lesdites compositions comprenant un ou plusieurs médicaments à administrer, et un copolymère thermoplastique greffé, ledit copolymère résultant de la réaction entre un macromonomère de polystyrène, possédant un groupe fonctionnel à insaturation éthylénique, et au moins un monomère hydrophile acide possédant un groupe fonctionnel à insaturation éthylénique.
Bereskin & Parr
Polytherapeutics Inc.
LandOfFree
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