Mucoadhesive drug delivery devices and methods of making and...

Details Mucoadhesive drug delivery devices and methods of making and... Mucoadhesive drug delivery devices and methods of making and...

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 9/00 (2006.01) A61M 31/00 (2006.01)

Patent

CA 2548822

The present invention relates to mucoadhesive drug delivery devices and their methods of preparation and use. More specifically the present invention relates to mucoadhesive drug delivery devices comprising one or more biocompatible purified proteins combined with one or more biocompatible solvents and one or more mucoadhesive agents. The mucoadhesive drug delivery devices may also include one or more pharmacologically active agents. The drug delivery devices of the present invention adhere to mucosal tissue, thereby providing a vehicle for delivery of the pharmacologically active agent(s) through such tissue.

L'invention concerne des dispositifs d'administration de médicaments mucoadhésifs ainsi que leurs procédés de préparation et d'utilisation. Plus précisément, l'invention concerne des dispositifs d'administration de médicaments mucoadhésifs comprenant au moins une protéine pure et biocompatible combinée à au moins un solvant biocompatible et au moins un agent mucoadhésif. Les dispositifs d'administration de médicaments mucoadhésifs peuvent également comporter au moins un agent pharmacologiquement actif. Les dispositifs d'administration de médicaments selon l'invention adhèrent aux tissus muqueux, fournissant ainsi un vecteur permettant d'administrer les agents pharmacologiquement actifs à travers ces tissus.

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