A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 31/196 (2006.01) A61K 31/415 (2006.01) A61K 31/57 (2006.01)
Patent
CA 2604768
Object of the invention are mucoadhesive and controlled release formulations consisting of aqueous solutions containing 0.05% to 5% by weight of a natural purified polymer having xyloglucan structure and 10% to 70% by weight of glycerol. These formulations are suitable for the application on human mucous membranes, such as nasal, oral and vaginal mucous membranes, as moisturizing and softening agents or as pharmaceutical release system. Further objects of the invention are pharmaceutical formulations and medical devices suitable for the application to human mucous membranes, containing the mucoadhesive and controlled release formulations together with active ingredients and excipients.
L~invention concerne des formulations mucoadhésives à libération contrôlée consistant en solutions aqueuses contenant de 0,05% à 5% en poids d~un polymère purifié naturel ayant une structure de xyloglucane et de 10% à 70% en poids de glycérol. Ces formulations sont adéquates pour l~application sur des membranes muqueuses humaines, telles que les membranes muqueuses nasale, orale ou vaginale, comme agents humidifiants et adoucissant ou comme système de libération pharmaceutique. L~invention concerne également des formulations pharmaceutiques et des dispositifs médicaux adéquats pour l~application sur des membranes muqueuses humaines, contenant les formulations mucoadhésives à libération contrôlée avec des ingrédients actifs et des excipients.
Bottoni Giuseppe
Caramella Carla
Federici Mascia
Maffei Paola
Rossi Silvia
Alfa Wassermann S.p.a.
Kirby Eades Gale Baker
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