Mucomimetic compositions and uses therefore

Details Mucomimetic compositions and uses therefore Mucomimetic compositions and uses therefore

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 31/728 (2006.01) A61K 31/785 (2006.01) A61K 47/02 (2006.01) A61K 47/34 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01) A61L 12/14 (2006.01)

Patent

CA 2737263

The present invention relates to mucomimetic and ophthalmic solutions comprising a cationic polymeric antimicrobial agent such as polyaminopropyl biguanide and a magnesium, calcium or magnesium/calcium complex of an anionic polymer such as hyaluronate, alginate, carboxymethyl cellulose, chondroitin sulfate or mixtures thereof. In specific embodiments, the solutions include additional components such as a surfactant, preferably polysorbate 20, a viscosity-modifying agent, preferably hydroxypropylmethyl cellulose, carboxymethyl cellulose or hydroxyethyl cellulose, a tonicity agent and a buffer. The solutions are biocompatible with and are highly comfortable when administered to mucous membranes, including those of the eye, as well as are effective disinfectants.

L'invention concerne des solutions mucomimétiques et ophtalmiques comprenant un agent antimicrobien polymère cationique ainsi que du biguanide de polyaminopropyle et un complexe de magnésium, de calcium ou de magnésium/calcium d'un polymère anionique tel que de lhyaluronate, de l'alginate, de la carboxyméthylcellulose, du sulfate de chondroïtine ou des mélanges de ces composés. Dans des modes de réalisation spécifiques, les solutions comprennent des constituants supplémentaires tels qu'un agent tensioactif, de préférence du polysorbate 20, un agent de modification de viscosité, de préférence de l'hydroxypropylméthylcellulose, de la carboxyméthylcellulose ou de l'hydroxyéthylcellulose, un agent de tonicité et un tampon. Les solutions sont biocompatibles avec les membranes des muqueuses, y compris celles de l'il, et sont très agréables lorsqu'elles leur sont administrées. Ce sont également des désinfectants efficaces.

Affiliated with

Also associated with

Rating

Mucomimetic compositions and uses therefore does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mucomimetic compositions and uses therefore, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mucomimetic compositions and uses therefore will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1819109