Mucosal bioadhesive slow release carrier for delivering...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/22 (2006.01) A61K 31/4178 (2006.01) A61K 31/4468 (2006.01) A61K 31/522 (2006.01)

Patent

CA 2647123

A mucosal bioadhesive slow release carrier comprising an active principle and devoid of starch, lactose, which can release the active principal for a duration of longer than 20 hours. This bioadhesive carrier contains a diluent, an alkali metal alkylsulfate, a binding agent, at least one bioadhesive polymer and at least one sustained release polymer, as well as a method for its preparation.

La présente invention concerne un vecteur muqueux bioadhésif à libération lente qui comprend un principe actif et qui est dépourvu d'amidon et de lactose, ledit vecteur pouvant libérer le principe actif pendant une durée supérieure à 20 heures. Ce vecteur bioadhésif contient un diluant, un alkylsulfate de métal alcalin, un agglutinant, au moins un polymère bioadhésif et au moins un polymère à libération prolongée. L'invention concerne également un procédé de préparation dudit vecteur.

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