Multi-applicable cell-culture method and apparatus

C - Chemistry – Metallurgy – 12 – M

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C12M 1/36 (2006.01) C12M 3/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2375209

A multi-applicable cell-culture method and apparatus, especially for the maintenance, proliferation, amplification or differentiation of cells in an enclosed space (10), comprising individual means (30,36) for adjusting flow and/or quantity in order to determine compositions and flows of mixtures of various components or nutritive media and compositions and flows of mixtures of various growth factors as envisaged above and for subsequent modification of said compositions and/or flows of mixtures of components or nutritive media and mixtures of growth factors supplied to said enclosed space, whereby said modifications can be performed independently from each other.

Procédé et dispositif de culture de cellules à applications multiples, en particulier pour l'entretien, la prolifération, l'amplification ou la différenciation de cellules dans une enceinte fermée (10), comprenant des moyens individuels (30, 36) de réglage de débit ou de quantité pour déterminer des compositions et des débits de mélanges de différents composants ou milieux nutritifs et des compositions et des débits de mélanges de différents facteurs de croissance, correspondant à l'une envisagée des applications précitées, et pour modifier ensuite les compositions et/ou les débits des mélanges de composants ou de milieux nutritifs et des mélanges de facteurs de croissance alimentant l'enceinte, ces modifications pouvant être effectuées indépendamment les unes des autres.

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