Multi-dimensional chromatographic methods for separating...

Details Multi-dimensional chromatographic methods for separating... Multi-dimensional chromatographic methods for separating...

B - Operations, Transporting

01

D

B01D 15/18 (2006.01) C07K 1/18 (2006.01) G01N 30/46 (2006.01)

Patent

CA 2682735

A multi-dimensional chromatographic method for the separation of N-glycans. The method comprises providing a glycan preparation that includes at least one negatively charged N-glycan. The glycan preparation is then separated by anion-exchange chromatography and at least one secondary chromatographic technique.

L'invention concerne un procédé de chromatographie multidimensionnelle permettant de séparer des N-glycanes. Le procédé comprend le fait de fournir une préparation de glycane qui inclut au moins un N-glycane négativement chargé. La préparation de glycane est ensuite séparée par une chromatographie d'échange anionique et par au moins une technique chromatographique secondaire.

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