Multi-lamellar liquid crystal emulsion system

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 277/82 (2006.01)

Patent

CA 2564506

Topical cosmetic and pharmaceutical oil-in-water emulsions wherein an emulsifier blend, comprising a mixture of at least two sucrose esters in combination with at least one solid fatty alcohol, forms a multi-lamellar liquid crystalline network that effectively moisturizes and protects the skin, and provides a useful vehicle for delivery of active ingredients. Sucrose esters are used in emulsions of the present invention at very low concentrations (from about 0.2% to about 1.2% by combined weight of sucrose esters relative to the total weight of the emulsion). SEQUENCE LISTING Not Applicable. Figure 1 shows a multi-lamellar liquid crystal emulsion system of the present invention under polarized light (200x). Figure 2 shows a multi- lamellar liquid crystal emulsion system of the present invention under polarized light (video 200x).

L'invention concerne des émulsions huile-eau cosmétiques et pharmaceutiques topiques dans lesquelles un mélange émulsifiant, renfermant un mélange d'au moins deux esters de saccharose en association avec au moins un alcool gras solide, forme un réseau cristallin liquide multi-lamellaire humidifiant et protégeant efficacement la peau, et permet d'obtenir un véhicule utile d'apport d'ingrédients actifs. Les esters de saccharose sont utilisés en émulsions de la présente invention à de très faibles concentrations (d'environ 0,2 % à environ 1,2 % en poids combiné d'esters de saccharose par rapport au poids total de l'émulsion).

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