Multi-modal optical tissue diagnostic system

Details Multi-modal optical tissue diagnostic system Multi-modal optical tissue diagnostic system

A - Human Necessities

61

B

A61B 5/00 (2006.01)

Patent

CA 2343401

The methods and apparatus according to the invention combine more than one optical modality, including but not limited to, fluorescence, absorption, reflectance, polarization anisotropy, and phase modulation to decouple morphological, biochemical changes associated with tissue changes, thus to provide an accurate diagnosis of the tissue's condition. The apparatus includes a transmit optical fiber bundle (52) to illuminate a target tissue, and optical fibers (54) to receive electromagnetic radiation returned from the target tissue. The processor device (44) analyzes the returned electromagnetic radiation to determine characteristics of the target tissue.

L'invention se rapporte à un appareil et à des procédés combinant une ou plusieurs modalités optiques, notamment et non exclusivement la fluorescence, l'absorption, la réflectance, l'isotropie de polarisation, et la modulation de phase, pour découpler des modifications morphologiques et biochimiques associées à des modifications tissulaires, et pour permettre un diagnostic précis de l'état d'un tissu. Ledit appareil comporte un faisceau de fibres optiques d'émission (52) et des fibres optiques (54) permettant de recevoir un rayonnement électromagnétique renvoyé par le tissu cible. Le dispositif de traitement (44) analyse le rayonnement électromagnétique renvoyé de manière à déterminer les caractéristiques du tissu cible.

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