G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/544 (2006.01) G01N 21/17 (2006.01) G01N 21/21 (2006.01) G01N 21/23 (2006.01) G01N 21/84 (2006.01) G01N 33/543 (2006.01) G01N 33/552 (2006.01)
Patent
CA 2098017
2098017 9210758 PCTABS00013 Apparatus and methods are provided for the detection of analytes. A polyunsaturated polymerized lipid layer (32) is employed, which is anisotropic, has a member of a specific binding pair bound to an end of the lipids, and whose optical characteristics are modified upon complex formation between the specific binding pair member and its complementary member. By providing for polarized light, linear and/or circular, one can detect the presence of complex formation by the change in the optical characteristics of the film (32). Polarizers (28, 42), analyzers (44, 52, 54), and wave plates (24, 40) are employed for providing for a light signal which can be analyzed and related to the presence of an analyte in a sample.
Choate Glenda L.
Guion Todd A.
Murdoch Joseph R.
Pan Victor
Ribi Hans O.
Biocircuits Corporation
Fetherstonhaugh & Co.
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