C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 16/46 (2006.01) C12N 15/62 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2732574
This disclosure provides a multi-specific fusion protein composed of a CD72- ligand binding domain and another binding domain specific for a heterologous target, such as a B-cell specific protein. The multi-specific fusion protein may also include an intervening domain that separates the other domains. This disclosure also provides polynucleotides encoding the multispecific fusion proteins, compositions of the fusion proteins, and methods of using the multi-specific fusion proteins and compositions.
La présente invention concerne une protéine hybride multi-spécifique constituée dun domaine de liaison au ligand CD72 et spécifique dun autre domaine de liaison pour une cible hétérologue, telle quune protéine spécifique du lymphocyte B. La protéine hybride multi-spécifique peut également comporter un domaine intermédiaire qui sépare les autres domaines. La présente invention concerne également des polynucléotides codant pour les protéines hybrides multi-spécifiques, des compositions des protéines hybrides, et des procédés dutilisation des protéines hybrides multi-spécifiques et des compositions.
Baum Peter Robert
Grosmaire Laura Sue
Tan Philip
Thompson Peter Armstrong
Emergent Product Development Seattle Llc
Mbm Intellectual Property Law Llp
LandOfFree
Multi-specific binding proteins targeting b cell disorders does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multi-specific binding proteins targeting b cell disorders, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multi-specific binding proteins targeting b cell disorders will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1913384