Multi-stage cascade boosting vaccine

Details Multi-stage cascade boosting vaccine Multi-stage cascade boosting vaccine

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 35/14 (2006.01) A61K 38/19 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C07K 16/42 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2448831

Humoral and cellular immune responses against tumor cells and infectious agents are induced in a mammal using a vaccine comprising antibodies and anti-idiotype antibodies that mimic an epitope of antigen that is associated with a tumor or infectious agent. Antibodies and cytokines also may be used to amplify the immune cascade. Moreover, antibodies and anti-idiotype antibodies can be used to produce T cells that are not MHC-restricted and that are targeted to tumor cells and infectious agents.

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