Multi-step method for the differentiation of insulin...

Details Multi-step method for the differentiation of insulin... Multi-step method for the differentiation of insulin...

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12N 5/16 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2494040

The present invention provides improved methods of differentiating insulin+, glucose responsive islet-like structures from insulin- cells. The invention further provides methods for using insulin+, glucose responsive islet-like structures, as well as the insulin+, glucose responsive cells which comprise said islet-like clusters.

La présente invention porte sur des procédés améliorés de différenciation des structures de type îlots sensibles à l'insuline+, au glucose à partir des cellules sécrétrices d'insuline. L'invention porte également sur des procédés d'utilisation de ces structures de type îlots sensible à l'insuline+, au glucose, ainsi que sur des cellules sensibles à l'insuline+, glucose comprenant ces groupes de type îlots.

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