C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) C12N 5/0783 (2010.01) A61K 39/21 (2006.01) A61K 48/00 (2006.01) C12N 7/00 (2006.01)
Patent
CA 2230029
The subject invention pertains to novel methods and compositions for protecting cats from infection by a broad range of FIV strains using a multi- subtype FIV vaccine. Multi-subtype FIV vaccines comprising either cell free whole virus or cell lines infected with viruses are described. Methods for vaccinating cats with the subject vaccine compositions are also described. Cats vaccinated according to the methods and compositions of the subject invention exhibit protective humoral and cellular immune responses to FIV when challenged with homologous or heterologous strains of FIV. The subject invention also pertains to novel feline cell lines that are susceptible to infection by FIV and their methods of use.
La présente invention concerne des procédés et des compositions de type nouveau destinés à protéger les chats de l'infection due à des souches virales FIV très variées, grâce à un vaccin contre le virus FIV à sous-classes multiples. Elle concerne également les vaccins proprement dits contre le virus FIV à sous-classes multiples, contenant soit un virus entier sans cellule, soit des lignées cellulaires infectées par des virus, ainsi que des procédés de vaccination des chats par administration desdites compositions. Les chats vaccinés selon ces procédés et ces compositions ont des réponses immunitaires humorales et cellulaires de protection contre le virus FIV quand ils sont exposés à des souches virales FIV homologues ou hétérologues.
Macrae & Co.
Regents Of The University Of California
University Of Florida
University Of Florida Research Foundation Inc.
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