Multichannel control in microfluidics

G - Physics – 01 – N

Patent

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G01N 27/447 (2006.01) B01L 3/00 (2006.01)

Patent

CA 2361923

Microfluidic devices are provided where barriers are introduced between different compartments of the device to prevent fluid flow between the two compartments. Different materials and methods are employed for the introduction and removal of the barriers, including reversible gel particle expansion, reversible gellation, in situ polymerization, magnetic beads, and the like. In this way mixing of agents may be temporally controlled during the operation of the device, where the barriers may be used in a passive manner or as an active agent involved in the operation being performed in the device.

L'invention concerne des dispositifs microfluidiques dans lesquels des barrières sont introduites entre différents compartiments du dispositif pour prévenir l'écoulement de fluide entre les deux compartiments. On utilise différents matériaux et procédés pour introduire et retirer les barrières, comme, par exemple l'expansion réversible de particules de gel, la geléfication réversible, la polymérisation in situ, les lits magnétiques et équivalent. Ainsi le mélange d'agents peut être temporairement commandé pendant le fonctionnement du dispositif, les barrières pouvant être utilisées de manière passive ou comme un agent actif impliqué dans l'opération réalisées dans le dispositif.

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