Multicomponent complex for use with a substrate

Details Multicomponent complex for use with a substrate Multicomponent complex for use with a substrate

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 45/08 (2006.01) A61K 51/12 (2006.01)

Patent

CA 2323016

Compositions and methods for use with substrates which are useful in the sustained delivery of bioeffecting agents are described. The compositions of the invention include a multicomponent complex which attaches a bioeffecting agent to a substrate with an anchor provided by a linker compound which also forms a cleavable linkage so that the bioeffecting agent's release into the area surrounding the substrate occurs in a sustained manner over an extended period of time. The methods of the invention involve providing a bioeffecting composition on the surface of a substrate so that a bioeffecting agent may be released in a sustained manner over time.

L'invention concerne des compositions et des procédés destinés à être utilisés avec des substrats utiles pour l'apport continu d'agents bioefficaces. Les compositions de l'invention comprennent un complexe multicomposant qui fixe un agent bioefficace à un substrat au moyen d'un élément d'ancrage fourni par un composé amorce formant également une liaison clivable de manière que la libération des agents bioefficaces dans une zone entourant le substrat se produise de manière continue sur une période de temps étendue. Les procédés de l'invention consistent à déposer une composition bioefficace à la surface d'un substrat de manière qu'un agent bioefficace puisse être libéré de manière continue dans le temps.

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