Multidirectional mucosal delivery devices and methods of use

A - Human Necessities – 61 – M

Patent

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A61M 37/00 (2006.01)

Patent

CA 2728912

The present invention relates to a pharmaceutical dosage form for transmucosal delivery of an active agent to two or more mucosal surfaces. The dosage form is presented as a transmucosal delivery device. The devices of the invention may in-clude at least two mucoadhesive surfaces. The devices may further include an intermediate layer disposed between the mucoadhe-sive layers. The pharmaceutical can be incorporated in any one or all of the mucoadhesive layers or the intermediate layer. Upon application, the device adheres to at least two surfaces, providing transmucosal delivery of the drug to at least two surfaces.

La présente invention concerne une forme pharmaceutique pour l'administration transmucosale d'un agent actif à au moins deux surfaces mucosales. La forme pharmaceutique se présente sous la forme d'un dispositif d'administration transmucosale. Les dispositifs selon l'invention peuvent comporrter au moins deux surfaces muco-adhésives. Ils peuvent également comporter une couche intermédiaire disposée entre les couches muco-adhésives. La forme pharmaceutique peut être incorporée dans l'une quelconque ou l'ensemble des couches muco-adhésives ou dans la couche intermédiaire. Lors de son application, le dispositif adhère à au moins deux surfaces, assurant une administration transmucosale du médicament à au moins deux surfaces.

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