Multifunctional adhesin proteins and their display in...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/10 (2006.01) B09C 1/10 (2006.01) C02F 1/28 (2006.01) C02F 3/34 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 14/24 (2006.01) C07K 14/245 (2006.01) C12N 1/21 (2006.01) C12N 11/00 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2330699

Recombinant cells expressing a multifunctional adhesin protein derived from a naturally occurring adhesin, containing a binding domain that is capable of binding to an organic receptor and a binding domain that is capable of binding to a compound to which the naturally occurring adhesin protein substantially does not bind. The cells or modified adhesin proteins, optionally in immobilized form, are useful for separating organic and inorganic compounds including toxic or precious metals from an environment.

Cette invention concerne des cellules recombinantes exprimant une protéine d'adhésine multifonctionnelle qui est dérivée d'une adhésine d'origine naturelle. Ces cellules recombinantes contiennent un domaine de liaison qui est capable de se lier à un récepteur organique, ainsi qu'un domaine de liaison qui est capable de se lier à un composé auquel la protéine d'adhésine d'origine naturelle ne se lie pratiquement pas. Ces cellules ou ces protéines d'adhésine modifiées, qui peuvent éventuellement se présenter sous une forme immobilisée, sont utiles afin d'extraire d'un milieu des composés organiques ou inorganiques, y compris des métaux précieux ou toxiques.

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