Multifunctional cox-2 inhibitors

Details Multifunctional cox-2 inhibitors Multifunctional cox-2 inhibitors

C - Chemistry, Metallurgy

12

Q

C12Q 1/26 (2006.01) A61K 31/365 (2006.01) A61K 31/405 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/4439 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/66 (2006.01)

Patent

CA 2495587

Selective inhibitors of COX-2 and selective inhibitors of COX-1 are screened for COX protein independent therapeutic activity. Compounds passing screening testing are indicated for treatment of those having or at risk for cancer, Alzheimer's disease and atherosclerosis.

L'invention concerne des inhibiteurs sélectifs de COX-2 et des inhibiteurs sélectifs de COX-1 que l'on crible à la recherche d'une activité thérapeutique indépendante de la protéine COX. Des composés ayant passé le test de criblage sont indiqués pour le traitement de ceux qui ont ou qui présentent le risque d'avoir le cancer, la maladie d'Alzheimer et l'athérosclérose.

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