C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 69/76 (2006.01) A61K 47/48 (2006.01) C07C 69/86 (2006.01) C07C 69/92 (2006.01) C07C 205/57 (2006.01) C07C 255/57 (2006.01) C07C 309/58 (2006.01) C07C 317/44 (2006.01) C07C 327/32 (2006.01) C07F 9/12 (2006.01) C07F 9/28 (2006.01) C07K 14/805 (2006.01)
Patent
CA 2195005
There are provided multifunctional chemical reagents useful in cross-linking proteins but having the capability of leaving two or more reaction sites available for further chemical reactions, after completion of the cross- linking process. These reagents can be broadly defined as aromatic compounds comprising an aromatic nucleus including but not limited to phenyl, biphenyl, naphthyl and binaphthyl (as herein defined), with at least four independently selected electronegative substituent groups bonded directly or indirectly to the aromatic nucleus.
L'invention se rapporte à des réactifs chimiques multifonctionnels utiles dans la réticulation de protéines, mais ayant la capacité de laisser deux sites de réaction ou plus disponibles pour d'autres réactions chimiques, une fois le processus de réticulation achevé. Ces réactifs peuvent être largement définis comme des composés aromatiques comprenant un noyau aromatique dans lequel il est possible de trouver, entre autres, phényle, biphényle, naphtyle et binaphtyle (comme définis), au moins quatre substituants électronégatifs choisis indépendamment étant liés directement ou indirectement au noyau aromatique.
Kluger Ronald H.
Paal Krisztina
Kluger Ronald H.
Paal Krisztina
Ridout & Maybee Llp
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