Multifunctional nanoscopy for imaging cells

Details Multifunctional nanoscopy for imaging cells Multifunctional nanoscopy for imaging cells

G - Physics

01

N

G01N 27/00 (2006.01) B82Y 5/00 (2011.01) B82Y 15/00 (2011.01) A61B 5/00 (2006.01) C12M 1/34 (2006.01) C12Q 1/00 (2006.01) C40B 60/00 (2006.01) G01D 5/14 (2006.01) G01D 5/16 (2006.01) H01L 27/00 (2006.01) H01L 27/20 (2006.01) H01L 29/84 (2006.01) H01L 23/52 (2006.01) H01L 29/20 (2006.01)

Patent

CA 2659674

Disclosed herein is an apparatus for sensing characteristics of an object. In a preferred embodiment, the apparatus comprises an array, wherein the array comprises a plurality of nanoscale hybrid semiconductor/metal devices which are in proximity to an object, each hybrid semiconductor/metal device being configured to produce a voltage in response to a perturbation, wherein the produced voltage is indicative of a characteristic of the object. Any of a variety of nanoscale EXX sensors can be selected as the hybrid semiconductor/ metal devices in the array. With such an array, ultra high resolution images of nanoscopic resolution can be generated of objects such as living cells, wherein the images are indicative of a variety of cell biologic processes.

L'invention concerne un dispositif pour détecter les caractéristiques d'un objet. Dans un mode préféré de réalisation, le dispositif comporte une matrice qui inclut une pluralité de dispositifs à semi-conducteur/métalliques hybrides nanoscalaires situés à proximité d'un objet, chacun desdits dispositifs étant conçu pour produire une tension en réponse à une perturbation ; la tension produite indique une caractéristique de l'objet. L'un quelconque des capteurs EXX nanoscalaires peut être sélectionné comme dispositif à semi-conducteur/métallique hybride dans la matrice. Ladite matrice peut générer des images ultra haute résolution d'une résolution nanoscopique d'objets, comme des cellules vivantes, les images indiquant une variété de processus biologiques de cellules.

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