C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2569202
The present invention provides the identification of genes that are expressed in tumors that are responsive to a given therapeutic agent and whose expression (either increased expression or decreased expression) correlates with responsiveness to that therapeutic agent. One or more of the genes of the present invention can be used as markers (or surrogate markers) to identify tumors that are likely to be successfully treated by that agent.
La présente invention fournit l~identification des gènes qui sont exprimés dans les tumeurs qui sont sensibles à un agent thérapeutique donné et dont l~expression (soit l~augmentation de l~expression, soit la diminution de l~expression) est en corrélation avec la sensibilité à cet agent thérapeutique. Un ou plusieurs des gènes de la présente invention peuvent être utilisés en tant que marqueurs (ou que marqueurs de substitution) pour identifier les tumeurs qui sont susceptibles d~être traitées avec succès par cet agent.
Ayers Mark
Hess Kenneth R.
Pusztai Lajos
Stec James
Symmans Fraser W.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Board Of Regents The University Of Texas System
Millenium Pharmaceuticals
LandOfFree
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