Multigene vectors

Details Multigene vectors Multigene vectors

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 48/00 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2323112

The present invention is directed to the use of particular gene combinations in genetic therapy. Delivery of multiple genes to a target cell at the same time augments the action of one or both genes. This is particularly effective in attacking diseased cells such as those making up hyperplastic or neoplastic tissues. Classes of genes that may be used in combination are tumor suppressors, cytokines and lymphokines, toxins, inducers of apoptosis, antisense oncogenes, single-chain antibodies, ribozymes, transcription factors and regulators, cell cycle regulators and enzymes.

L'invention concerne l'utilisation de combinaisons géniques particulières en thérapie génique. L'administration de multiples gènes dans une cellule cible augmente en même temps l'action d'un ou deux gènes. Ceci s'avère particulièrement efficace pour attaquer les cellules malades telles que celles formant des tissus hyperplasiques ou néoplasiques. Des constructions géniques susceptibles d'être utilisées de manière combinées sont des suppresseurs de tumeur, des cytokines et lymphokine, des toxines, des inducteurs d'apoptose, des oncogènes antisens, des anticorps à unichaîne, des ribozymes, des facteurs de transcription et des régulateurs, des régulateurs de cycles des cellules et des enzymes.

Affiliated with

Also associated with

Rating

Multigene vectors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Multigene vectors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multigene vectors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1657608