Multilayer membrane useful as synthetic skin

C - Chemistry – Metallurgy – 08 – J

Patent

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18/16, 28/0.55

C08J 9/00 (2006.01) A61F 2/10 (2006.01) A61L 15/22 (2006.01) A61L 27/24 (2006.01) A61F 2/00 (2006.01)

Patent

CA 1071814

ABSTRACT OF THE DISCLOSURE A multilayer membrane, which is useful as synthetic skin, is disclosed herein. A first layer is formed from a material which does not provoke an immune response and which is also insoluble and nondegradable in the presence of body fluids and/or body enzymes. Preferred materials for the first layer are crosslinked composites of collagen and a mucopolysaccharide. A second layer is formed from a nontoxic material which controls the moisture flux of the overall membrane to about 0.1 to 1 mg./cm2/hr. Suitable materials for the second layer includes syn- thetic polymers such as silicone resins, polyacrylate or poly- methacrylate esters or their copolymers, and polyurethanes.

256972

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