C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 9/127 (2006.01) A61K 47/48 (2006.01) C07K 14/47 (2006.01) C07K 14/73 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2063593
2063593 9117170 PCTABS00008 This invention relates to multimeric and hetero-multimeric gelsolin fusion constructs, compositions containing them and methods using them. More particularly, this invention relates to multimeric gelsolin fusion constructs in which at least two gelsolin fusion polypeptides are bound to vesicles containing polyphosphoinositides. This invention also relates to gelsolin fusion polypeptides which comprise gelsolin moieties linked to functional moieties and in particular, to CD4-gelsolin fusion polypeptides comprising an amino acid sequence for a human CD4 protein linked to a gelsolin moiety.
Pepinsky R. Blake
Rosa Margaret D.
Stossel Thomas P.
Biogen Inc.
Pepinsky R. Blake
Rosa Margaret D.
Smart & Biggar
Stossel Thomas P.
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