Multimeric ligands with enhanced stability

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) A61K 38/17 (2006.01) A61K 38/22 (2006.01) A61K 38/27 (2006.01) C07K 14/575 (2006.01) C07K 14/61 (2006.01) C07K 14/72 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2483330

The present invention provides compositions and methods for making multimeric proteins to increase stability over their monomer. For example, more stable growth hormone and prolactin receptor agonists are provided.

La présente invention concerne des compositions et des procédés de fabrication de protéines multimères de façon à améliorer la stabilité sur leur monomère. Cette invention concerne par exemple une hormone de croissance plus stable et des agonistes de récepteur de prolactine.

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