C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) C07H 21/04 (2006.01) C07K 16/00 (2006.01) C07K 16/46 (2006.01) C12N 15/10 (2006.01) C12N 15/82 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2499891
The invention described herein encompasses (1) artificial preproteins and the polynucleotides encoding them, (2) methods for producing these biomolecules, and (3) methods for their use. The artificial preproproteins of this invention comprise a protein assembly capable of producing a multimeric protein from a single protein. Figure 4 illustrates generally the process by which a polynucleotide encoding the artificial preproprotein is introduced into a cell and a biomolecule of interest is produced.
La présente invention concerne (1) des préprotéines artificielles et des polynucléotides codant pour ces préprotéines; (2) des procédés permettant de produire ces biomolécules; et (3) des procédés permettant de les utiliser. Les préprotéines artificielles décrites dans cette invention comprennent un ensemble protéique capable de produire une protéine multimérique à partir d'une seule protéine. La figure 4 illustre, d'une manière générale, le processus au cours duquel un polynucléotide codant pour la préprotéine artificielle est introduit dans une cellule, et au cours duquel ladite biomolécule est produite.
Edwards Patricia
Reinl Stephen J.
Kentucky Bioprocessing Llc
Large Scale Biology Corporation
Smart & Biggar
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