A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 38/17 (2006.01) A61L 27/60 (2006.01) A61P 9/00 (2006.01) A61P 17/02 (2006.01) A61P 39/00 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2693383
The present invention provides a multimeric form of a Tie 2 binding peptide monomer, wherein the multimeric form has Tie 2 agonist activity. The multimeric form, preferably a tetramer, stimulates angiogenesis and promotes wound healing. The present invention also features pharmaceutical compositions comprising the multimeric Tie 2 agonists, including those suitable for topical or systemic administration. Methods of using the multimeric Tie 2 agonists of the invention for stimulating angiogenesis and for promoting healing of wounds, such as diabetic ulcers or skin grafts, are also provided.
La présente invention concerne une forme multimère d'un monomère de peptide de liaison Tie 2, ladite forme multimère ayant une activité d'agoniste de Tie 2. La forme multimère, de préférence un tétramère, stimule l'angiogenèse et favorise la guérison des blessures. La présente invention concerne également des compositions pharmaceutiques comprenant les agonistes de Tie 2 multimères, notamment ceux qui sont appropriés pour une administration topique ou systémique. L'invention concerne également des procédés d'utilisation des agonistes de Tie 2 multimères selon l'invention pour stimuler l'angiogenèse et pour favoriser la guérison des blessures, par exemple les ulcères diabétiques ou les greffes de peau.
Dumont Daniel
Van Slyke Paul
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sunnybrook Health Sciences Center
LandOfFree
Multimeric tie 2 agonists and uses thereof in stimulating... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multimeric tie 2 agonists and uses thereof in stimulating..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multimeric tie 2 agonists and uses thereof in stimulating... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1384308