A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01)
Patent
CA 2551662
The present invention is directed to multiparticulate formulations for oral use, preferably comprising one or more therapeutically active agents. In particular, the present invention relates to fast melt formulations which are capable of masking the taste of the active agent, by virtue of one or more tastemasking measures, whilst retaining the desired drug dissolution profile and good mouthfeel. The multiparticulate formulations of the invention can be used in a multiple dose delivery device which dispenses a unit dose of the powder upon actuation, or can be packaged for dispensation in sachets or like unit dose containers.
La présente invention concerne des préparations multiparticulaires pour administration orale, comprenant de préférence un ou plusieurs principes actifs. Cette invention concerne en particulier des préparations à dissolution rapide capables de masquer de diverses manières le goût du principe actif, tout en conservant le profil de dissolution et une sensation agréable en bouche. Les préparations mutliparticulaires de l'invention peuvent s'utiliser dans un dispositif d'administration multidose qui permettent d'administrer une dose unitaire de poudre par activation, ou qui peuvent être présentées en sachets ou conditionnements unitaires analogues.
Morton David
Simpson David
Staniforth John
Pharmakodex Limited
Sim & Mcburney
Vectura Limited
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