Multiparticulate osmotic delivery system

Details Multiparticulate osmotic delivery system Multiparticulate osmotic delivery system

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2655596

The invention relates to a pharmaceutical composition, comprising at least one micropartide comprising at least one core which is at least partially coated with at least one osmotic subcoat, and at least one outer coat which at least partially coats the at least one osmotic subcoat, wherein said at least one core comprises at least one drug, and at least one excipient, and said at least one osmotic subcoat comprises at least one osmotic agent and at least one osmotic deposition vehicle.

La présente invention concerne une composition pharmaceutique qui comprend au moins une microparticule ayant au moins un noyau enrobé au moins partiellement par au moins une sous-couche osmotique et au moins une couche externe qui enrobe au moins partiellement la ou les sous-couches osmotiques. Le ou les noyaux comprennent au moins un médicament et au moins un excipient et ladite ou lesdites sous-couches osmotiques comprennent au moins un agent osmotique et au moins un véhicule/excipient de dépôt par osmose.

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