Multiple acting anti-angiogenic and cytotoxic compounds and...

Details Multiple acting anti-angiogenic and cytotoxic compounds and... Multiple acting anti-angiogenic and cytotoxic compounds and...

C - Chemistry, Metallurgy

07

D

C07D 491/048 (2006.01) A61K 31/519 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2722197

This invention discloses pyrimidine compounds, and pharmaceutically acceptable salts, solvates and prodrugs thereof, useful in therapeutically and/or prophylactically treating patients with cancer by inhibiting receptor tyrosine kinases and/or dihydrofolate reductase and/or thymidylate synthase. The compounds, and methods of using these compounds, are disclosed.

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