Multiple active pharmaceutical ingredients combined in...

Details Multiple active pharmaceutical ingredients combined in... Multiple active pharmaceutical ingredients combined in...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2615378

The present disclosure describe inhalation particles where each discrete unagglomerated inhalation particle comprising 2 or more active pharmaceutical ingredients. In one embodiment, the inhalation particles comprise a first and a second API where the second API covers, at least partially, and protects the first API from degradation or instability. Inhalation particles comprising a first and a second API as described herein have many advantages over present means of delivering two or more APIs. Formulations comprising such inhalation particles are also described.

Ces particules d'inhalation présentent chacune sous forme non agglomérée deux ou plusieurs principes actifs pharmaceutiques. Selon une variante, les particules comprennent une première et une seconde API, la seconde recouvrant, au moins partiellement, et protégeant la première API contre la dégradation ou l'instabilité. Les particules d'inhalation comprennent des première et seconde API remarquables, par rapport à l'état actuel de la technique, par la capacité d'administrer au moins deux API. Les formulations contiennent de telles particules d'inhalation.

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