Multiple antigenic peptide displaying multiple copies of an...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) A61K 39/00 (2006.01) A61P 43/00 (2006.01) C07K 14/36 (2006.01) C07K 14/465 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2450783

The present invention relates to an antigenic product for inducing an immune response to a deposit-forming polypeptide, such as amyloid .szlig., which antigenic product is a multiple antigenic peptide (MAP) that contains multiple copies of an epitope of a deposit-forming polypeptide involved in a plaque- forming disease. This antigenic product can be formulated into an immunizing composition and used to elicit an immune response against a deposit-forming polypeptide involved in a plaque-forming disease or disorder.

La présente invention concerne un produit antigénique pour induire une réaction immunitaire à un polypeptide formant des dépôts tel que l'amyloïde .szlig., ledit produit antigénique constituant un peptide antigénique multiple (MAP) qui contient des copies multiples d'un épitope d'un polypeptide formant des dépôts impliqué dans des maladies à formation de plaques. Le produit antigénique peut être formulé comme une composition d'immunisation et utilisé pour éliciter une réaction immunitaire contre un polypeptide à formation de plaques impliqué dans des maladies ou troubles à formation de plaques.

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