Multiple array system for integrating bioarrays

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 11/02 (2006.01) B01L 3/00 (2006.01) C12M 1/22 (2006.01) C12M 1/34 (2006.01) C12N 11/06 (2006.01) C12N 11/08 (2006.01) C12N 11/14 (2006.01) G01N 33/543 (2006.01) G06T 7/00 (2006.01)

Patent

CA 2429056

A multiple level micro-array system for integrating micro-arrays of biomolecules, including biological, chemical and biochemical elements. The multiple level micro-arrays are formed using soft lithography techniques and elastomeric membranes (1)b) to shield or pattern various portions of a suitable substrate (3) with biomolecules (8). Additional levels are formed using membranes (4) with various through holes (5) which either isolate, stratify or shield the patterned biomolecules from subsequent patterning or addition of an array solution.

L'invention concerne un système de microréseaux à plusieurs niveaux pour intégrer des microréseaux de biomolécules, comprenant des éléments biologiques, chimiques et biochimiques. Les microréseaux à plusieurs niveaux sont formés au moyen de techniques de lithographie douce et de membranes élastomères pour protéger ou structurer différentes parties d'un substrat adéquat avec des molécules. Des niveaux additionnels sont formés au moyen de membranes dotées de trous de passage qui isolent, stratifient ou protègent les biomolécules structurées contre une structuration ultérieure ou une addition d'une solution de dosage.

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