Multiple drug resistance gene atrd of aspergillus nidulans

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) C07K 14/38 (2006.01) A61K 38/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2315531

The invention provides isolated nucleic acid compounds encoding a multiple drug resistance protein of Aspergillus nidulans. Vectors and transformed host cells comprising the multiple drug resistance-encoding DNA of Aspergillus nidulans atrD are also provided. The invention further provides assays which utilize these transformed host cells.

L'invention se rapporte à des composés d'acides nucléiques isolés codant une protéine de multirésistance médicamenteuse d'Aspergillus nidulans. L'invention se rapporte également à des vecteurs et à des cellules hôtes transformées comportant l'ADN codant la multirésistance médicamenteuse d'Aspergillus nidulans, atrD. Enfin, l'invention se rapporte à des analyses mettant en oeuvre ces cellules hôtes transformées.

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