Multiple fluorescence labelling with europium chelators

Details Multiple fluorescence labelling with europium chelators Multiple fluorescence labelling with europium chelators

C - Chemistry, Metallurgy

12

N

195/35, 167/43,

C12N 11/02 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)

Patent

CA 1330061

ABSTRACT A conjugate for use in a labelling system comprises avidin or streptavidin linked to a carrier particle, having more than fifteen amino groups on its surface, which are individually capable of being labelled with an operable label. The carrier particle is capable of being linked to the avidin or streptavidin to form the conjugate. The conjugate is particularly useful in forming a fluorescent reagent system. The carrier particle is labelled with a plurality of ligand moieties forming with a lanthanide metal ion, fluorescent chelates attached to the plurality of amino groups to provide at least fifteen labels. The fluorescent reagent system, when excited to fluoresce, emits fluorescent radiation with an intensity amplified compared to intensity of fluorescent radiation emitted by the plurality of fluorescent lanthanide metal ion chelate moieties in a solution whereby the fluorescent reagent is void of any quenching effects due to multiple labelling in the fluorescent reagent system. The fluorescent labelling system is particularly useful in binding assays.

599628

Affiliated with

Also associated with

Rating

Multiple fluorescence labelling with europium chelators does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Multiple fluorescence labelling with europium chelators, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multiple fluorescence labelling with europium chelators will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1305032