Multiple fusion probes

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/04 (2006.01) C07H 21/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2314426

A method of detecting reciprocal gene translocations by employing multiple probe sets which span the breakpoint regions and encompass regions on both sides of each breakpoint of the translocation on each chromosome involved in the translocation. Probe sets and diagnostic kits for the method are also disclosed.

L'invention concerne un procédé de détection de translocations de gènes réciproques au moyen d'ensembles sondes multiples couvrant les régions de cassure et entourant les régions de chaque côté de la cassure de translocation, sur chaque chromosome affecté par la translocation. L'invention porte également sur des ensembles sondes et des kits de diagnostic.

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