Multiple injector flow through dissolution cell, for...

Details Multiple injector flow through dissolution cell, for... Multiple injector flow through dissolution cell, for...

G - Physics

01

N

73/92

G01N 1/14 (2006.01) G01N 13/00 (2006.01) G01N 33/15 (2006.01) G01N 35/00 (2006.01)

Patent

CA 1128335

MULTIPLE INJECTOR FLOW THROUGH DISSOLUTION CELL FOR DISSOLUTION TESTING APPARATUS Abstract A dissolution cell for use in automatic dis- solution testing apparatus is specially configured to accommodate the iterative insertion of product specimens into the dissolution mechanism flow stream, and to perform the specimen insertion into a stabilized flow stream with minimal insertion disturbance. A basic multiple-injection embodiment utilizes a linear configuration to selectively insert two specimens into the flow stream, and a circular multiple-injection embodiment teaches the selective insertion of a plurality of specimens into the stream in a manner amenable to a program- mable sequence. Both embodiments use air evacu- ation of the specimen flow chamber prior to its insertion into the instrumented flow stream, and both allow a high degree of fidelity in the dis- solution measurements performed. The improved cell is especially useful for testing rapidly dis- solving industrial products or drug dosage forms.

380335

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