Multiple reactor system and method for polynucleotide synthesis

Details Multiple reactor system and method for polynucleotide synthesis Multiple reactor system and method for polynucleotide synthesis

C - Chemistry, Metallurgy

07

H

23/375, 195/1.12

C07H 21/00 (2006.01) B01J 19/00 (2006.01)

Patent

CA 1204680

33 MULTIPLE REACTOR SYSTEM AND METHOD FOR POLYNUCLEOTIDE SYNTHESIS ABSTRACT OF THE DISCLOSURE A reactor system and method for synthesizing or degrading polynucleotides and other linear polymers includes a tubular reactor connected to a reagent mani- fold. The polynucleotide is immobilized on a loosely packed solid-phase support material in the tubular reac- tor, and reagents are sequentially introduced into the tubular reactor. After each reagent is introduced, the tubular reactor is isolated from the reagent manifold and the reagent agitated-by alternately pressurizing the opposite ends of the tubular reactor. The method provides rapid and efficient synthesis of polynucleo- tides. By connecting two or more tubular reactors to the reagent manifold, a plurality of polynucleotides having different sequences may be synthesized simulta- neously. CCCCC5/9729-6-1

456838

Affiliated with

Also associated with

Rating

Multiple reactor system and method for polynucleotide synthesis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Multiple reactor system and method for polynucleotide synthesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multiple reactor system and method for polynucleotide synthesis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1204853