Multiple-rnai expression cassettes for simultaneous delivery...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/04 (2006.01) A01N 43/04 (2006.01) C12N 5/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2606002

The present invention provides compositions and methods suitable for expressing y-x multiple-RNAi agents against an allele or alleles of interest in cells, tissues or organs of interest in vitro and in vivo so as to treat diseases.

L'invention porte sur des préparations et méthodes d'expression d'agents d'ARNi multiples anti-allèle ou anti-allèles d'intérêt dans des cellules, tissus ou organes d'intérêt, in vitro et in vivo, en vue du traitement de maladies.

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