Multiple sequential polynucleotide displacement reactions...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2309384

Methods for determining the presence of a target polynucleotide sequence using chemical hybridization in sequential probe and displacement complex formation with potential for signal gain prior to detection are disclosed.

L'invention concerne des procédés permettant de détecter la présence d'une séquence polynucléotidique cible grâce à une hybridation chimique dans un complexe sonde à déplacement séquentiel, qui présente un potentiel de gain de signal avant toute détection.

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