C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/00 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2335277
The present invention encompasses novel splice variant forms of the mu-opioid receptor-1 (MOR-1) and the polynucleotide sequences encoding the MOR-1 splice variants. The invention further encompasses methods of screening for compositions regulating the MOR-1 splice variant activities and the development of therapeutic modalities directed to regulating activity. Regulation of the MOR-1 splice variant activities may impact the physiologic processes of analgesia and weight management.
La présente invention concerne de nouvelles formes de variants d'épissage du récepteur mu-opioïde 1 (MOR-1) et les séquences polynucléotidiques codant pour les variants d'épissage de MOR-1. L'invention concerne en outre des procédés de criblage de compositions régulant les activités de variants d'épissage de MOR-1 et la mise au point de modalités thérapeutiques visant à réguler ces activités. La régulation d'activités de variants d'épissage de MOR-1 peut avoir un effet sur les processus physiologiques d'analgésie et de gestion du poids.
Pan Ying-Xian
Pasternak Gavril
Memorial Sloan-Kettering Cancer Center
Smart & Biggar
LandOfFree
Multiple splice variants of the mu-opioid receptor gene does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multiple splice variants of the mu-opioid receptor gene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multiple splice variants of the mu-opioid receptor gene will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1343028